Zenas BioPharma, Inc., a clinical-stage biopharma company, engages in the development and commercialization of transformative immunology-based therapies. Its lead product candidate is obexelimab, a bifunctional monoclonal antibody designed to bind CD19 and Fc?RIIb for the treatment of various I&I diseases and various indications, including immunoglobulin G4-related disease, multiple sclerosis, and systemic lupus erythematosus. The company develops ZB002, an anti-TNFa monoclonal antibody; ZB004, a CTLA-4-Ig fusion protein designed to have an extended half-life versus; and ZB001, an anti-IGF-1R monoclonal antibody. The company was formerly known as Zenas BioPharma (Cayman) Limited and changed its name to Zenas BioPharma, Inc. in August 2023. The company was incorporated in 2019 and is headquartered in Waltham, Massachusetts. Show more

852 Winter Street, Waltham, MA, 02451, United States

Biotechnology
Healthcare

Market Cap

1.338B

52 Wk Range

$6.11 - $44.60

Previous Close

$20.36

Open

$20.12

Volume

1,722,639

Day Range

$19.81 - $22.15

Enterprise Value

826.2M

Cash

343.2M

Avg Qtr Burn

-52.41M

Insider Ownership

24.43%

Institutional Own.

70.29%

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date

BLA

Submission

Orelabrutinib (BTK Inhibitor) Details
Primary Progressive Multiple Sclerosis

Phase 3

Update

Orelabrutinib (BTK Inhibitor) Details
Secondary Progressive Multiple Sclerosis

Phase 3

Initiation

Obexelimab (CD19xFcyRIIb) Details
Systemic lupus erythematosus

Phase 2

Data readout

Orelabrutinib (BTK Inhibitor) Details
Systemic Lupus Erythematosus

Phase 2

Update

Phase 2

Update

ZB021 (IL-17AA/AF Inhibitor) Details
Rheumatic And Dermatologic Diseases

Phase 1

Initiation

Obexelimab (CD19xFcyRIIb) Details
Warm autoimmune hemolytic anemia

Failed

Discontinued