X4 Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases of the immune system. It offers XOLREMDI, an orally small-molecule selective antagonist of chemokine receptor CXCR4, which is in phase 3 clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome. It has a license agreement with Abbisko Therapeutics Co Ltd. to manufacture and distribute XOLREMDI in mainland China, Taiwan, Hong Kong and Macau; Norgine to develop, manufacture, and commercialize mavorixafor in Europe, Australia, and New Zealand; and Genzyme Corporation for CXCR4 receptor to develop and commercialize products containing licensed compounds for all therapeutic, prophylactic and diagnostic uses. The company is headquartered in Boston, Massachusetts. Show more
61 North Beacon Street, Boston, MA, 02134, United States
Market Cap
385.5M
52 Wk Range
$1.35 - $6.96
Previous Close
$4.35
Open
$4.23
Volume
206,099
Day Range
$4.17 - $4.44
Enterprise Value
219.8M
Cash
253M
Avg Qtr Burn
-15.53M
Insider Ownership
0.63%
Institutional Own.
90.29%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Mavorixafor (CXCR4 inhibitor) Details WHIM Syndrome | Approved Quarterly sales | |
Mavorixafor (CXCR4 inhibitor) Details Severe Congenital Neutropenia | Phase 3 Data readout | |
Mavorixafor (CXCR4 inhibitor) Details Chronic Neutropenia | Phase 2 Update | |
Mavorixafor (CXCR4 inhibitor) + ibrutinib Details Waldenstrom macroglobulinemia | Failed Discontinued | |
Mavorixafor (CXCR4 inhibitor) Details Renal cell carcinoma, Cancer | Failed Discontinued |
