Tectonic Therapeutic, Inc., a biotechnology company, focuses on the discovery and development of therapeutic proteins and antibodies to modulate the activity of G protein coupled receptors (GPCRs). It develops GEODe technology platform to enable the discovery and development of GPCR-targeted biologic medicines. The company's lead product is TX45, a Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone, and relaxin. It is also developing TX2100 for the treatment of hereditary hemorrhagic telangiectasia; GPCR modulator bispecific for treating fibrosis; and other GPCR modulators. The company is headquartered in Watertown, Massachusetts. Show more

490 Arsenal Way, Watertown, MA, 02472, United States

Biotechnology
Healthcare

Market Cap

514.9M

52 Wk Range

$14.39 - $36.03

Previous Close

$27.29

Open

$27.37

Volume

180,770

Day Range

$27.10 - $28.87

Enterprise Value

281.5M

Cash

236.9M

Avg Qtr Burn

-18.41M

Insider Ownership

39.34%

Institutional Own.

74.13%

Qtr Updated

03/31/26


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Drug & IndicationStage & EventCatalyst Date
TX45 Details
Pulmonary Hypertension (PH) associated with Interstitial Lung Disease (ILD)

Phase 2

Data readout

TX45 Details
Pulmonary hypertension in Heart failure with preserved Ejection Fraction (PH-HFpEF)

Phase 2

Data readout

TX45 Details
Pulmonary hypertension in Heart failure with preserved Ejection Fraction (PH-HFpEF)

Phase 2

Data readout

TX45 (RXFP1 Agonist) Details
Pulmonary Hypertension In Heart Failure With Reduced Ejection Fraction (PH-HFrEF)

Phase 1b

Data readout

TX2100 Details
Hereditary Hemorrhagic Telangiectasia (HHT)

Phase 1a

Data readout