Akari Therapeutics, Plc, an oncology company, develops antibody-drug conjugates (ADC) for cancer-killing toxins. Its lead payload is PH1 to disrupt the function of spliceosomes and to trigger an immune response that leads to additional cancer cell killing. The company's lead product candidate is AKTX-101, a preclinical stage trop2-targeting ADC that combines PH1 with the trop2 antibody to treat solid tumor cancer types, including lung, breast, bladder, head and neck, gastric, pancreatic, colon, prostate, and others. Its payloads include PH1 is a novel payload that is a spliceosome modulator designed to disrupt RNA splicing within cancer cells. The company also develops AKTX-102, a novel bispecific ADC that utilizes PH1 as its payload to treat various solid tumor cancers. Akari Therapeutics, Plc is headquartered in Tampa, Florida. Show more
401 East Jackson Street, Tampa, FL, 33602, United States
Market Cap
4.006M
52 Wk Range
$3.02 - $56.80
Previous Close
$3.50
Open
$3.34
Volume
26,310
Day Range
$3.26 - $3.88
Enterprise Value
2.911M
Cash
5.203M
Avg Qtr Burn
-3.041M
Insider Ownership
24.56%
Institutional Own.
5.93%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Nomacopan Details Paroxysmal nocturnal hemoglobinuria | Phase 3 Update | |
Nomacopan Details Hematopoietic stem cell transplantation thrombotic microangiopathies | Phase 3 Initiation | |
Nomacopan Details COVID-19 | Phase 2 Update | |
Nomacopan Details Atopic Keratoconjunctivitis | Phase 1/2 Update | |
AKTX-101 (Spliceosome Modulator) Details K-Ras G12V Mutated Pancreatic Ductal Adenocarcinoma | Phase 1 Initiation | |
Nomacopan Details Geographic atrophy, Eye disease | Phase 1 Initiation | |
Nomacopan Details Bullous pemphigoid | Failed Discontinued |
